Provoque topical serum is the future of aesthetic regenerative treatment and the key to reawakening the skin’s own natural renewal system. This breakthrough treatment is backed by over 20+ years of peer-reviewed science and is gentle, effective, and safe to use every day for all skin types.
Provoque is a next-generation regenerative serum powered by the complete skin secretome—a powerful combination of growth factors, exosomes, and the exclusive protein fetuin-A.
The only option in the market that’s ethically sourced from a single FDA-approved human stem cell line, Provoque targets the visible signs of aging by stimulating your skin’s natural repair process at the cellular level.
Unlike other serums that isolate growth factors or exosomes alone, Provoque leverages the full regenerative power of the skin’s secretome—including the clinically validated protein fetuin-A. This protein supports collagen production, reduces inflammation, and enhances skin firmness by stimulating repair pathways at the cellular level.
Treatments can be used on the face, neck, and body—including the arms, abdomen, and knees—to help tighten and smooth without needles or surgery.
A clinical study of topical application of Provoque over 12 weeks shows significant improvement in seven key skin metrics (table below)
Peer reviewed published data:
Provoque is safe and effective for a wide range of skin types and ages, especially for patients noticing early signs of aging or mild-to-moderate skin laxity. Because the treatment is noninvasive and customizable, it’s a great fit for patients who want natural-looking results without discomfort or downtime.